Evaluating Effectiveness and Long Term Safety of Damoctocog Alfa Pegol in Patients, Who Have Been Diagnosed With Hemophilia A

Study Identifier:
20002
ClinicalTrials.gov Identifier:
EudraCT Identifier:
N/A
Sponsor:
Bayer
Collaborator:
N/A
Study Contact Information:
N/A
Unmapped

Study Details

Medical Condition
  • Hemophilia A
Study Drug
  • Drug: Damoctocog alfa pegol (Jivi, Bay94-9027)
Date
Oct 2019 - Dec 2026
Phase 1
Phase 2
Phase 3
Phase 4
N/A
Patient Requirements
Sex: Female & Male
Age: N/A - N/A years
Requirements Information

Protocol Summary

This study is looking at how safe it is to switch from emicizumab to Mim8, in people with haemophilia A. Mim8 is a new medicine that is used to prevent bleeding episodes in people with haemophilia A. Mim8 works by replacing the function of the missing clotting factor VIII (FVIII). Mim8 will be injected under the skin using a pen-injector either once every week, once every two weeks or once every month. The participants will be trained in using the pen injector. The participants can choose themselves, in collaboration with the study doctor how often they get Mim8 in this study. When the participant will get their first Mim8 injection depends on their current treatment with emicizumab. The participants will get their first Mim8 injection at Visit 2. Participants will have between 6 and 27 Mim8 injections. The total number of injections participants will have depends on their dosing frequency. The study will last for about 6-12 months. While taking part in this study, there are some restrictions about what medicine participant can use. The study doctor will tell the participants more about this. In case the participants experience bleeds, these can be treated with additional haemostatic medicine as agreed with the study doctor. Female participants cannot take part if they are pregnant, breast-feeding or plan to get pregnant during the study period.

Trial Locations

Location
Status
Location
South Alabama Medical Science Foundation
Mobile, Alabama, United States, 36688
Status
N/A
Location
Banner MD Anderson Cancer Center
Phoenix, Arizona, United States, 85012
Status
N/A
Location
University California Davis
Davis, California, United States, 95616
Status
N/A
Location
Orthopaedic Hospital DBA Orthopaedic Institute for Children
Los Angeles, California, United States, 90007
Status
N/A
Location
The Center for Comprehensive Care and Diagnosis of Inherited Blood Disorders
Orange, California, United States, 92868
Status
N/A
Location
University of Colorado Hemophilia and Thrombosis Center
Aurora, Colorado, United States, 80045
Status
N/A