Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors

Study Identifier:
NN7415-4311
ClinicalTrials.gov Identifier:
EudraCT Identifier:
N/A
Sponsor:
Novo Nordisk A/S
Collaborator:
N/A
Study Contact Information:
N/A
Unmapped

Study Details

Medical Condition
  • Hemophilia A With Inhibitor(s)
Study Drug
  • Drug: Concizumab
Date
Oct 2019 - Dec 2021
Phase 1
Phase 2
Phase 3
Phase 4
N/A
Patient Requirements
Sex: Male
Age: N/A - N/A years
Requirements Information

Protocol Summary

This study is looking at how safe it is to switch from emicizumab to Mim8, in people with haemophilia A. Mim8 is a new medicine that is used to prevent bleeding episodes in people with haemophilia A. Mim8 works by replacing the function of the missing clotting factor VIII (FVIII). Mim8 will be injected under the skin using a pen-injector either once every week, once every two weeks or once every month. The participants will be trained in using the pen injector. The participants can choose themselves, in collaboration with the study doctor how often they get Mim8 in this study. When the participant will get their first Mim8 injection depends on their current treatment with emicizumab. The participants will get their first Mim8 injection at Visit 2. Participants will have between 6 and 27 Mim8 injections. The total number of injections participants will have depends on their dosing frequency. The study will last for about 6-12 months. While taking part in this study, there are some restrictions about what medicine participant can use. The study doctor will tell the participants more about this. In case the participants experience bleeds, these can be treated with additional haemostatic medicine as agreed with the study doctor. Female participants cannot take part if they are pregnant, breast-feeding or plan to get pregnant during the study period.

Trial Locations

Location
Status
Location
Center for Inherited Blood Dis
Orange, California, United States, 92868
Status
N/A
Location
Children's Healthcare Atlanta
Atlanta, Georgia, United States, 30329
Status
N/A
Location
Indiana Hemophilia-Thromb Ctr
Indianapolis, Indiana, United States, 46260
Status
N/A
Location
Washington University School of Medicine_St. Louis
Saint Louis, Missouri, United States, 63110
Status
N/A
Location
St. Jude Affiliate Clinic at Novant Health Hemby Children's
Charlotte, North Carolina, United States, 28204
Status
N/A
Location
TriStar Medical Group Children's Specialist
Nashville, Tennessee, United States, 37203
Status
N/A